Research Interests
- Pulmonary Vascular Disease
- Dry Powder Inhalers; Spray Drying; Inhalation
- Monocrotaline; Type II Bone Morphogenetic Protein Receptor; Pulmonary Hypertension
- Renalase; NAD(P)H Oxidase (H2o2-forming); Apocynin
- Myosin Light Chain Kinase; Cadherin 5; ML 7
- Persistent Fetal Circulation Syndrome; Ductus Arteriosus; Pulmonary Hypertension
Abstracts
Peer-reviewed Publications
Noteworthy Publications
- Bertero, Thomas ; Lu, Yu ; Annis, Sofia; Hale, Andrew; Bhat, Balkrishen; Saggar, Rajan; Saggar, Rajeev; Wallace, W. Dean; Ross, David J.; Vargas, Sara O.; Graham, Brian B. ; Kumar, Rahul ; Black, Stephen M; Fratz, Sohrab; Fineman, Jeffrey R. ; West, James D.; Haley, Kathleen J.; Waxman, Aaron B. ; Chau, B. Nelson; Cottrill, Katherine A. ; Chan, Stephen Y. Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. Journal of Clinical Investigation; 2014 Aug 1; 124(8): 3514–3528. PMID: 24960162
- Bertero, Thomas; Cottrill, Katherine A ; Yu Lu ; Haeger, Christina M; Dieffenbach, Paul; Annis, Sofia; Hale, Andrew; Bhat, Balkrishen; Kaimal, Vivek ; Zhang, Ying-Yi ; Graham, Brian B; Kumar, Rahul; Saggar, Rajan; Saggar, Rajeev; Wallace; W Dean; Ross, David J; Black, Stephen M; Fratz, Sohrab; Fineman, Jeffrey R; Vargas, Sara O; Haley, Kathleen J; Waxman, Aaron B; Chau, B Nelson; Fredenburgh, Laura E; Chan, Stephen Y. Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Reports; 2015 Nov 3; 13(5) 1016-1032. PMCID: PMC4644508 PMID: 26565914
- Tang, Haiyang; Babicheva, Aleksandra; McDermott, Kimbery M.; Gu, Yali; Ayon, Ramon J.; Song, Shanshan; Wang, Ziyi; Gupta, Akash, Zhou, Tong; Xutong, Sun; Dash, Swetaleena; Wang, Zilu; Balistrieri, Angela; Zheng, Qiuyu; Cordery, Arlette G.; Desi, Ankit A.; Rischard, Franz; Khalpey, Zain; Wang, Jian; Black, Stephan M.; Garcia, Joe G.N.; Makino; Ayako; and Yuan, Jason X.-J. Endothelial HIF-2 alpha contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition. American Journal of Physiology-Lung Cellular and Molecular Physiology; 2018 Feb 1; 314(2) L256-L275. PMID: 29074488
- Rafikov, Rusian; Sun, Xutong; Rafikova, Olga; Meadows, Mary Louise; Desai, Ankit A.; Khalpey, Zain; Yuan, Jason X.-J.; Fineman, Jeffrey R.; and Black, Stephen M., Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells. Redox Biology; 2015, Jul 3; (6) 278-286. PMID: 26298201
- Lu, Qing; Harris, Valerie A.; Kumar, Sanjv; Mansour, Heidi M.; and Black, Stephen M., Autophagy in neonatal hypoxia ischemic brain is associated with oxidative stress. Redox Biology; 2015 Dec (6) 516-523. PMID: 26454246
Education
- Ph.D. in Molecular Pharmacology, University of Edinburgh, Scotland
Professional Honors
- 1998 James A. Shannon Director’s Award, The National Institutes of Health
- 2000 March of Dimes Basic Research Award
- 2007 Distinguished Faculty Award for Basic Science Research, Medical College of Georgia, School of Medicine
- 2011 Regent’s Professor, Georgia Regent’s University
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