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The faculty at CTS bring together many research areas, along with expertise and accomplishment in those areas. Our researchers collaborate on national and international levels, bringing the best researchers together to benefit the advancement of the understanding of human disease, leading to the improvement of human health, through translational and regenerative medical research.
Dr. Black’s research is focused on the understanding of the mechanisms underlying the development of endothelial dysfunction that precedes the development of pulmonary hypertension, the role of reactive oxygen species in this process, and the understanding of how decreased nitric oxide signaling leads to the pulmonary vascular remodeling that is associated with more advanced disease.
Dr. Cao’s research is focused on understanding the pathological mechanisms underlying spinal cord injury (SCI) and developing the stem cell based therapeutic strategies to promote regeneration and functional recovery after SCI. Using SCI models, his lab has been investigating the therapeutic potential of different neural progenitor cells, including neural stems cells, neuronal- and glial-restricted precursor cells and oligodendrocyte precursor cells.
Dr. Giulianotti’s research is focused on synthetic chemistry, including extensive use of computational chemistry to augment SAR discovery, the design of hit optimization, purification and chemical characterization, and metabolic studies.
Dr. Gu’s research is focused on mass spectrometry (MS)-based metabolomics and its applications in early disease diagnosis, drug metabolism, and biological sciences. We are skilled in the development, optimization, and applications of MS methods for both qualitative and quantitative measurements.
Dr. Kim’s research is focused on the development and biological/ pharmacological characterization of small molecule inhibitors targeting the proteasome-ubiquitin pathway.
Dr. Liu’s research is focused on stem cell biology and regenerative medicine, and pathogenesis of neurodegenerative disease and central nervous system injury. We use genetic and molecular and cellular biological approaches to dissect the developmental pathways and the corresponding pathogenesis in the neural lineage, specifically for spinal cord injury and stroke. Our long-term goal is to provide novel therapeutic approaches for the treatment of CNS injury and neurodegenerative diseases.
The Mansour Lab opened at FIU CTS in February 2022 after nearly 9 years at The University of Arizona. The Mansour Lab has successfully provided advanced training to 13 Postdoctoral Research Scholars, numerous health professional and engineering students, and has graduated 5 doctoral graduate students with PhD degrees.
To learn more about the innovative research in the Mansour Lab, please see these publications.
Dr. Marciano’s research is focused on investigating mechanisms of extracellular vesicle signaling in the vasculature and their application as therapeutics, biomarkers, and molecular tools.
Dr. Nefzi’s research is focused on the design and synthesis of small molecules and heterocyclic combinatorial libraries, mixture-based chemical libraries for the identification of highly active antimicrobial compounds, potent analgesic, and novel anti-tumor agents.
Dr. Pinilla’s research is focused on two areas, the identification of small molecule selective MC3agonist, utilizing the previously identified small molecules as well as new positional scanning libraries, and characterization and elucidation of the antigen specificity of anti-hellminth Memory of Tfh and Th2 cell repertoireans.
Dr. Wang’s research is focused on environmental health research including cardiopulmonary toxicity of particulate matter air pollution, lung biology of acute lung injury and asthma, as well as lung genomics and genetics.
Dr. Xia‘s laboratory is focused on neurodegenerative diseases; amyotrophic lateral sclerosis; Parkinson’s disease; human genetics; mutant rats; molecular biology.
Dr. Zemskov’s research is focused on the molecular mechanisms associated with endothelial barrier protections using in vitro and in vivo models of acute lung injury (ALI) and ventilator -induced lung injury (VLI).
Dr. Zhou‘s laboratory is focused on neurodegenerative diseases; amyotrophic lateral sclerosis; gene manipulation in rat model; neurochemistry; molecular biology.
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