Eun Young Choi, PhD
Research Assistant Professor
Office: CTS 307/308
Email: euchoi@fiu.edu
FIU Discovery
Overview
Dr. Choi is currently a Research Assistant Professor at the Center for Translational Science (CTS) of Florida International University. Dr. Choi obtained her Ph.D. in Biophysics from the Ohio State University and then gained postdoctoral training under Professor Frank Slack (now at Beth Israel Deaconess Medical Center, Harvard University) at Yale University Department of Molecular Cellular and Developmental Biology. Dr. Choi then moved to the University of Kentucky, Lexington, KY, where she investigated the mechanism of inflammation modulated by the ubiquitin-proteasome system (UPS). Her current research is focused on understanding the role of the immunoproteasome in the pathophysiology of inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn’s disease, and its treatment using immunoproteasome inhibitors.
Research Interests
Delineation of immunoproteasome functions in inflammatory bowel diseases (IBD). Development of immunoproteasome inhibitors for IBD treatment. Development of a novel class of proteasome inhibitors for multiple myeloma patients who have developed resistance to existing drugs, including the first-generation and second-generation proteasome inhibitors bortezomib (Velcade®) and carfilzomib (Kyprolis®), respectively.