Marcello Giulianotti, Ph.D.
Principal Scientist
Office of Research and Economic Development
FIU Center for Translational Science
Office: Remote
Email: mgiulian@fiu.edu
Overview
Dr. Giulianotti is currently a Principal Scientist at the FIU Center for Translational Science. He received his BS in Chemistry/Biochemistry from UCSD, his MBA from SDSU and his PhD in Chemistry from USF. Dr. Giulianotti’s research focuses on applying novel techniques in combinatorial and computational chemistry for the identification of hit compounds as well as hit to lead optimization. He employs technologies that allow for the rapid assessment of millions of small molecules and peptides using exponentially less samples. The technology can be applied to virtually any assay paradigm. Dr. Giulianotti’s group currently have active programs in the areas of obesity, cachexia, neurite outgrowth, tachyphylaxis, diabetic kidney disease, and bacterial resistance. We are always open to new collaborations as well as discussing advancements in the use of our core capabilities.
Prior to joining FIU Dr. Giulianotti worked for 25 years at the Torrey Pines Institute for Molecular Studies where he held several research and business development positions. Additionally, Dr. Giulianotti served as a Program Director with the International Space Station (ISS) U.S. National Laboratory. Part of his activities in this role included managing the Chips in Space programs cosponsored by the National Center for Advancing Translational Sciences and National Institute of Biomedical Imaging and Bioengineering as well as the Tissue Engineering and Mechanobiology in Space Programs cosponsored by the National Science Foundation. Currently Dr. Giulianotti is a Senior Manager at Sierra Space. His primary efforts there are focused on positively impacting humankind by advancing transformative technologies in the area of in-space biomanufacturing.
Research Interests
Peptide libraries, library screening, small molecule libraries, medicinal chemistry, computational chemistry, hit to lead
Recent Publications
Research Interests
- Pulmonary Vascular Disease
- Dry Powder Inhalers; Spray Drying; Inhalation
- Monocrotaline; Type II Bone Morphogenetic Protein Receptor; Pulmonary Hypertension
- Renalase; NAD(P)H Oxidase (H2o2-forming); Apocynin
- Myosin Light Chain Kinase; Cadherin 5; ML 7
- Persistent Fetal Circulation Syndrome; Ductus Arteriosus; Pulmonary Hypertension
Abstracts
Education
Professional Honors
