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Publications

Dr. Wang’s most recent publications.

  1. Nitration of protein kinase G-Ialpha modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: implications for acute lung injury. Zemskov EA, Wu X, Aggarwal S, Yegambaram M, Gross C, Lu Q, Wang H, Tang H, Wang T, Black SM. Journal of Biological Chemistry 2021 Jul 9:100946. doi: 10.1016/j.jbc.2021.100946. Online ahead of print.PMID: 34252457
  2. Identification of S1PR3 gene signature involved in survival of sepsis patients. Feng A, Ma W, Faraj R, Kelly GT, Black SM, Fallon MB, Wang T. BMC Medical Genomics 2021 Feb 6;14(1):43. doi: 10.1186/s12920-021-00886-2.PMID: 33549110
  3. Anti-inflammatory Effects of Statins in Lung Vascular Pathology: From Basic Science to Clinical Trials. Faraj R, Paine D, Black SM, Wang T. Advances in Experimental Medicine and Biology 2021;1303:33-56. doi: 10.1007/978-3-030-63046-1_3.PMID: 33788186
  4. RAC1 nitration at Y(32) IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury. Wang T, Yegambaram M, Gross C, Sun X, Lu Q, Wang H, Wu X, Kangath A, Tang H, Aggarwal S, Black SM. Redox Biology 2021 Jan;38:101794. doi: 10.1016/j.redox.2020.101794. Epub 2020 Nov 13.PMID: 33248422
  5. A mutation found in esophageal cancer alters integrin beta4 mRNA splicing. Kelly GT, Faraj R, Dai Z, Cress AE, Wang T. Biochemical and Biophysical Communications 2020 Aug 27;529(3):726-732. doi: 10.1016/j.bbrc.2020.06.078. Epub 2020 Jul 19.PMID: 32736699
  6. Remote Ischemic Conditioning Reduced Acute Lung Injury After Traumatic Brain Injury in the Mouse. Saber M, Rice AD, Christie I, Roberts RG, Knox KS, Nakaji P, Rowe RK, Wang T, Lifshitz J. Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches 2021 Feb 1;55(2):256-267. doi: 10.1097/SHK.0000000000001618.PMID: 32769821
  7. S1PR1-Associated Molecular Signature Predicts Survival in Patients with Sepsis. Feng A, Rice AD, Zhang Y, Kelly GT, Zhou T, Wang T. Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches 2020 Mar;53(3):284-292. doi: 10.1097/SHK.0000000000001376.PMID: 32045395
  8. Pulmonary Endothelial Mechanical Sensing and Signaling, a Story of Focal Adhesions and Integrins in Ventilator Induced Lung Injury. Kelly GT, Faraj R, Zhang Y, Maltepe E, Fineman JR, Black SM, Wang T. Frontiers in Physiology 2019 Apr 26;10:511. doi: 10.3389/fphys.2019.00511. eCollection 2019.PMID: 31105595
  9. Complex interplay between autophagy and oxidative stress in the development of pulmonary disease. Ornatowski W, Lu Q, Yegambaram M, Garcia AE, Zemskov EA, Maltepe E, Fineman JR, Wang T, Black SM. Redox Biology 2020 Sep;36:101679. doi: 10.1016/j.redox.2020.101679. Epub 2020 Aug 11.PMID: 32818797
  10. Activation of the mechanosensitive Ca(2+) channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics. Lu Q, Zemskov EA, Sun X, Wang H, Yegambaram M, Wu X, Garcia-Flores A, Song S, Tang H, Kangath A, Cabanillas GZ, Yuan JX, Wang T, Fineman JR, Black SM. Redox Biology 2021 Jan;38:101785. doi: 10.1016/j.redox.2020.101785. Epub 2020 Nov 12.PMID: 33221570
  11. Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system. Wu X, Sun X, Sharma S, Lu Q, Yegambaram M, Hou Y, Wang T, Fineman JR, Black SM. Nitric Oxide Journal 2021 Mar 1;108:12-19. doi: 10.1016/j.niox.2020.12.003. Epub 2020 Dec 15.PMID: 33338599
  12. TGF-beta1 attenuates mitochondrial bioenergetics in pulmonary arterial endothelial cells via the disruption of carnitine homeostasis. Sun X, Lu Q, Yegambaram M, Kumar S, Qu N, Srivastava A, Wang T, Fineman JR, Black SM. Redox Biology 2020 Sep;36:101593. doi: 10.1016/j.redox.2020.101593. Epub 2020 May 31.PMID: 32554303
  13. Hemodynamic Alterations for Pulmonary Artery Remodeling. Johnson Kameny R, Datar SA, Boehme JB, Morris C, Zhu T, Goudy BD, Johnson EG, Galambos C, Raff GW, Sun X, Wang T, Chiacchia SR, Lu Q, Black SM, Maltepe E, Fineman JR. American Journal of Respiratory Cell and Molecular Biology 2019 May;60(5):503-514. doi: 10.1165/rcmb.2018-0305MA.PMID: 30620615
  14. Biomechanical Forces and Oxidative Stress: Implications for Pulmonary Vascular Disease. Zemskov EA, Lu Q, Ornatowski W, Klinger CN, Desai AA, Maltepe E, Yuan JX, Wang T, Fineman JR, Black SM. Antioxid Redox Signal 2019 Oct 20;31(12):819-842. doi: 10.1089/ars.2018.7720. Epub 2019 Mar 19.PMID: 30623676
  15. RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression. Liu P, Rojo de la Vega M, Sammani S, Mascarenhas JB, Kerins M, Dodson M, Sun X, Wang T, Ooi A, Garcia JGN, Zhang DD. Proceedings of the National Academy of Sciences U.S.A.2018 Oct 30;115(44):E10352-E10361. doi: 10.1073/pnas.1812125115. Epub 2018 Oct 11.PMID: 30309964
  16. Potential Diagnostic Power of Blood Circular RNA Expression in Active Pulmonary Tuberculosis. Qian Z, Liu H, Li M, Shi J, Li N, Zhang Y, Zhang X, Lv J, Xie X, Bai Y, Ge Q, Ko EA, Tang H, Wang T, Wang X, Wang Z, Zhou T, Gu W. EBioMedicine 2018 Jan;27:18-26. doi: 10.1016/j.ebiom.2017.12.007. Epub 2017 Dec 8.PMID: 29248507
  17. Myosin light chain kinase ( MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions. Wang T, Brown ME, Kelly GT, Camp SM, Mascarenhas JB, Sun X, Dudek SM, Garcia JGN. Pulmonary Circulation 2018 Apr-Jun;8(2):2045894018764171. doi: 10.1177/2045894018764171. Epub 2018 Feb 26.PMID: 29480069
  18. The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor beta Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression. Brown RV, Wang T, Chappeta VR, Wu G, Onel B, Chawla R, Quijada H, Camp SM, Chiang ET, Lassiter QR, Lee C, Phanse S, Turnidge MA, Zhao P, Garcia JGN, Gokhale V, Yang D, Hurley LH. Journal of the American Chemical Society 2017 Jun 7;139(22):7456-7475. doi: 10.1021/jacs.6b10028. Epub 2017 May 19.PMID: 28471683
  19. Non Muscle myosin light chain kinase activity modulates radiation-induced lung injury. Wang T, Mathew B, Wu X, Shimizu Y, Rizzo AN, Dudek SM, Weichselbaum RR, Jacobson JR, Hecker L, Garcia JG. Pulmonary Circulation 2016 Jun;6(2):234-9. doi: 10.1086/686491.PMID: 27252850
  20. Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets. Wang T, Gross C, Desai AA, Zemskov E, Wu X, Garcia AN, Jacobson JR, Yuan JX, Garcia JG, Black SM. American Journal of Physiology-Lung Cellular and Molecular Physiology 2017 Apr 1;312(4):L452-L476. doi: 10.1152/ajplung.00231.2016. Epub 2016 Dec 15.PMID: 27979857