Prakash Chaudhari, PhD
PostDoctoral Associate
Office: CTS 266
Phone: 772-345-4736
Email: pchaudha@fiu.edu
Scholars: Google Scholar
Overview
Dr. Prakash Dilip Chaudhari holds an M.Sc. in Drug Chemistry from the University of Pune, Maharashtra, India, and furthered his academic journey by earning a Ph.D. in synthetic organic chemistry with a focus on asymmetric synthesis from the National Chung Cheng University (NCCU), Taiwan.
Following the completion of his Ph.D., Dr. Prakash contributed to academia and research as a postdoctoral fellow at both National Chung Cheng University and National Taiwan University in Taiwan, as well as at Louisiana State University (LSU), USA.
In addition to his academic pursuits, Dr. Prakash has hands-on industry experience. Prior to pursuing his Ph.D., he accumulated 5 years of valuable experience in various pharmaceutical companies, where he specialized in API process development. This background provided him with a practical understanding of pharmaceutical operations.
Dr. Prakash also worked to the drug discovery field during his tenure at Aragen Life Sciences (formerly known as GVK). Serving as an Associate Scientist in the drug discovery department.
Research Interests
Design and synthesis of small molecules and heterocyclic combinatorial libraries. As well as mixture-based chemical libraries for identification of highly active antimicrobial compounds, potent analgesic, and novel anti-tumor agents.
Recent Publications
1.Parallel Synthesis of Piperazine Tethered Thiazole Compounds with Antiplasmodial Activity”.
Int. J. Mol. Sci. 2023, 24, 17414
2.Polyheterocyclic peptidomimetics: Parallel solid phase synthesis of oligo cyclic guanidines and their inhibition activity against Mycobacterium tuberculosis DNA Gyrase”
Bioorganic & Medicinal Chemistry Letters 93, 2023, 129439
3.From Citronellal to Iridoids. Asymmetric Syntheses of Iridoids and Their Analogues Via Organocatalytic Intramolecular Michael Reactions.
Org. Biomol. Chem., 2023, 21, 4200-4205.
4.Cyclopentane Oxindoles Containing Four Consecutive stereocenters and Quaternary α-Nitro Esters via Organocatalytic Enantioselective Michael–Michael Cascade Reactions.
ACS Omega, 2019, 4, 655–667.
5. “The azatryptophan-based fluorescent platform for in vitrorapid screening of inhibitors disrupting IKKβ-NEMO interaction.”
Bioorganic Chemistry, 2018, 81, 504–511.
6.“Organocatalytic Enantiselective Michael-Michael-Michael-Aldol Condensation Reactions: Control of Six Stereocenters in a Quadruple- Cascade Asymmetric Synthesis of Polysubstituted Spirocyclic Oxindoles.”
Organic Letters, 2017, 19, 6112–6115.
